Welcome to the Miyamoto group!
Our major research project is the analysis of various biological functions
and the development of usuful biocatalysts suitable for industrial applications.
Please enjoy to explore our web-site to get a more detailed description
of the group.
You can download the reprint entitled "A bacterium that degrades
and assimilates poly(ethylene terephthalate)" in Science.
Reprint
Yoshida et al. Science (2016) Accepted Version.pdf
Science provided a link to our published manuscript online. Anyone can
access the published paper free of charge by clicking on this link. Access
is only granted to that specific paper.
慶應義塾大学COI-NEXTキックオフシンポジウム(鎌倉商工会議所)
視聴はこちらから
以下の論文か掲載・受理されました
(1) S. K. Gaßmeyer, J. Wetzig, C. Mügge, M. Assmann, J. Enoki, L. Hilterhaus,
R. Zuhse, K. Miyamoto, A. Liese and R. Kourist
JST「共創の場形成支援プログラム(COI-NEXT)」
多くのメディアに取り上げて頂きました
国内メディア
NHK、フジテレビ、毎日放送、朝日新聞、読売新聞、産経新聞、京都新聞、日刊工業新聞、化学工業日報、財経新聞 他多数
国外メディア
The Wall Street
Journal
The Guardian
newspaper : London
ABC Science : the
Australian Broadcasting Corporation's science website
Chemistry World :
Royal Society of Chemistry's magazine
Fusion in NYC
American Association for the Advancement of Science
(AAAS):Scienceの出版元のWebサイト
Chemical &
Engineering News
Discovery News : Washington
New Scientist
magazine : London
De Volkskrant,
leading non-tabloid newspaper : Netherlands
UOL : the main
Brazilian news website
CorreioBraziliense
: the brazilian newspaper
Basque newspaper
Berria
Spanish news agency
SINC
PBS NewsHour : Washington
The daily newspaper
La Vanguardia, : Barcelona
他多数
Publication
A bacterium that degrades and assimilates
poly(ethylene terephthalate)
Science 351, 1196 (2016)
Feeding on plastic
A bacterium completely degrades
poly(ethylene terephthalate)
By Uwe T. Bornscheuer(私の留学時代の恩師による紹介記事です)
Science 351, 1154 (2016)
M. Bartsch, S. K. Gaßmeyer, K. Köninger, K. Igarashi, P. Liauw, N. Dyczmons-Nowaczyk,
K. Miyamoto, M. M. Nowaczyk and R. Kourist
Microb. Cell Fact., 14(1), 53 (2015)
S. Yoshida, J. Enoki, R. Hemmi, R. Kourist,
N. Kawakami and K. Miyamoto
Genome Announc., May/June, 3 (3), e00373-15
(2015)
K. Yuki, M. Ikeda, S. Yoshida, O. Ohno, K.
Suenaga, K. Yamada, D. Uemura and K. Miyamoto
Isolation of monovalerianester A, an
inhibitor of fat accumulation, from Valeriana fauriei
Natural Product Commun., 10 (8), 1333 –
1334 (2015)
N. Kawakami, Y. Hara and K. Miyamoto
Modulating the catalytic activity and the
substrate specificity of alcohol dehydrogenases using cyclic ethers
Catal. Sci. Technol., 5(8), 3922-3925
(2015)
S. Yoshida, J. Enoki, R. Kourist and K.
Miyamoto
Engineered hydrophobic pocket of
(S)-selective arylmalonate decarboxylase variant by simultaneous saturation
mutagenesis to improve catalytic performance
Biosci. Biotechnol. Biochem., in press
S. K. Gaßmeyer, H. Yoshikawa, J. Enoki, N.
Hülsemann, R. Stoll, K. Miyamoto and R. Kourist
STD-NMR based protein engineering of the
unique arylpropionate-racemase AMDase G74C
ChemBioChem, in press
R. Wada, M. Ozaki, T. Kumon, H. Ohta and K.
Miyamoto
Substrate specificity of an archaeon
Sulfolobus tokodaii esterase bearing a GGG(A)X motif
Biocatal. Biotransformation, accepted for
publication
Book chapters
Cofactor recycling using a thermostable
NADH oxidase
Hirano, Jun-ichiro; Ohta, Hiromichi;
Yoshida, Shosuke; Miyamoto, Kenji
Edited by Ekinci, Deniz
Chemical Biology (2012), 63-82.
Asymmetric decarboxylation of arylmalonates
and racemization of profens by arylmalonate decarboxylase and its variants
Miyamoto, Kenji; Kourist, Robert; Yoshida,
Shosuke; Ohta, Hiromichi
Edited by Whittall, John; Sutton, Peter W
Practical Methods for Biocatalysis and Biotransformations 2 (2012), 274-280.
Patent
Preparations of hyper-active arylmalonate
decarboxylase variants for (S)-form selective prodn. of α-arylpropionic acids
Miyamoto, Kenji
PCT Int. Appl. (2012), WO 2012117999 A1
20120907
Kenji Miyamoto
PCT WO2010098505
Kenji Miyamoto and Hiromichi Ohta
US2011/0045548
Kenji Miyamoto
Thermally driven asymmetric decarboxylation
using a thermostable esterase as a chiral space
16th Japanese-German Workshop on Enzyme Technology,Kyoto University
2015年9月
Enzyme engineering of a bacterial decarboxylase for the production of fine chemicals
Kenji Miyamoto, Active Enzyme Molecule 2014
Dramatically improved catalytic activity of an artificial (S)-selective
arylmalonate decarboxylase by structure-guided directed evolution, Kenji
Miyamoto
Asymmetric Decarboxylation by Arylmalonate Decarboxylase and Thermostable
Esterase, Kenji Miyamoto,Gordon Research Conference (Biocatalysis) 2010年7月 Bryant University (USA)
〒223-8522
神奈川県横浜市港北区日吉3-14-1
慶應義塾大学理工学部
矢上キャンパス14棟520B号室
TEL.045-566-1786
3-14-1 Hiyoshi, Yokohama 223-8522 Japan
Department of Biosciences and Informatics, Keio University
Tel. +81-45-566-1786
Office : Room 520B, BuildingNo.14